The role of IGF-1 in exercise to improve obesity-related cognitive dysfunction

Obesity is an important factor that threatens human health. The occurrence of many chronic diseases related to obesity, and cognitive function decline often occurs with the onset obesity. With further prevalence it bound lead a wider range dysfunction (ORCD). Therefore, crucial suppress ORCD through intervention. In this regard, exercise has been shown be effective in preventing obesity improving as non-drug treatment. There sufficient evidence regulatory effect on growth closely function—insulin-like 1 (IGF-1). IGF-1 may mediator exercise. This article reviews effects regulation IGF-1. It analyzes mechanism by which can improve regulating Overall, review provides from relevant animal studies studies, showing plays role ORCD. emphasizes importance IGF-1, helps understand health promotes research treatment